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Measuring nanoparticles with the new HORIBA LB-550V from Retsch Technology

With the Horiba LB-550V, Retsch Technology GmbH is now offering an innovative analyzer for particle size analysis by dynamic scattered light measurement in the range from 1 nm to 6000 nm even at high concentrations.

In particle technology the trend is to ever-smaller particles. Pharmaceuticals, biotechnology, materials technology, semiconductor industry, cosmetics and more other industrial branches are experiencing revolutionary impulses from the production and processing of nanoparticles.
For the reliable characterization of such particles Retsch Technology can now provide the optimal solution with the HORIBA LB-550V.
The LB-550V makes it possible to measure the size of particles in the range from 1 nm up to 6000 nm throughout a wide concentration range from a few ppm up to 40% by volume.

Convincing advantages:

- Backscattering signals are recorded by a highly sensitive detector. As a result of the detector arrangement both low concentrations of suspensions of weakly scattering particles, such as proteins and polymers, as well as more highly concentrated suspensions and emulsions can be measured. The graph provided as an example shows the plot of a trimodal polystyrene/latex (PSL) standard that has been resolved without any problems.

- Recording homodyne measuring signals in combination with a Fourier transformation algorithm for calculating the particle size distribution. This technique leads to a demonstrably improved resolution for measurements of broad, even non-monomodal distributions.

- Built-in viscometer and Peltier element for thermostatting the measuring cell. Optionally the viscosity, an important evaluation parameter, can be measured directly in the instrument.

- Short analysis times of 1-2 minutes guarantee high sample throughput. At the same time an intuitive, user-friendly software ensures both flexibility and routine use. The software is 21 CFR Part 11-compatible.

- Very simple and flexible sampling handling by the use of disposable cuvets with volumes of 100 µl and more or alternatively a flow-through measuring cell.